Bone Resorption by Felix Bronner, Mary C. Farach-Carson, Janet Rubin

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By Felix Bronner, Mary C. Farach-Carson, Janet Rubin

This booklet displays the meteoric raise in wisdom concerning bone home improvement together with molecular knowing of osteoclast improvement, regulatory molecules similar to cytokines, pathophysiology and pharmaceutical improvement to regard osteoclast functionality. fast ebook of an updated quantity addressing those matters by means of specialists within the box, an asset to any library of medical endocrinologists and rheumatologists, might be a beneficial learn for these getting into the medical enviornment of bone home improvement study. it's going to combine fresh technological advances with starting place information to supply a complete view of bone resorption, and also will hyperlink details won from the genetic and molecular to the physiological and scientific degrees This quantity is addressed to medical practitioners, food scientists, researchers and scholars, who search a primary figuring out of this significant topic. a useful booklet for the neighborhood of clinical experts- internists, endocrinologists, nephrologists, orthopaedists- in addition to dental, paramedical, nursing and veterinary practitioners. valuable additionally for these getting into the sector of bone biology, in addition to these at the research/clinical interface who locate it tough to discover an entire sequence to carry them ?up to hurry? with technological developments during this zone.

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Chiellini C, Costa M, Novelli SE, Amri EZ, Benzi L, Bertacca A, et al. (2003) Identification of cathepsin K as a novel marker of adiposity in white adipose tissue. J Cell Physiol 195:309–21. 16. Delaisse JM, Andersen TL, Engsig MT, Henriksen K, Troen T, Blavier L (2003) Matrix metalloproteinases (MMP) and cathepsin K contribute differently to osteoclastic activities. Microsc Res Tech 61:504–13. 17. Delaisse JM, Boyde A, Maconnachie E, Ali NN, Sear CH, Eeckhout Y, et al. (1987) The effects of inhibitors of cysteine-proteinases and collagenase on the resorptive activity of isolated osteoclasts.

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2000) Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis. J Exp Med 192:463–74. 122. Miyauchi A, Kuroki Y, Fukase M, Fujita T, Chihara K, Shiozawa S (1994) Persistent expression of protooncogene c-fos stimulates osteoclast differentiation. Biochem Biophys Res Commun 205:1547–55. 123. Mochizuki H, Hakeda Y, Wakatsuki N, Usui N, Akashi S, Sato T, et al. (1992) Insulin-like growth factor-I supports formation and activation of osteoclasts.

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