Bone Diseases: Macroscopic, Histological, and Radiological by Claus-Peter Adler

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By Claus-Peter Adler

The ebook offers a finished description of macroscopic, microscopic, and radiological equipment for the prognosis of bone illnesses. It provides all the methods focused on analysis, utilizing not just radiological and histological recommendations, but additionally smooth immunohistochemical and scintigraphic tools. Succinct and well-structured healing suggestions are supplied for an array of bone ailments. A practice-oriented reference paintings for pathologists, radiologists, rheumatologists, and orthopedists.

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Extra resources for Bone Diseases: Macroscopic, Histological, and Radiological Diagnosis of Structural Changes in the Skeleton

Sample text

6b, the crystals are hexagonal (5) and are embedded alongside the collagen fibrils at intervals of 68 nm. They stabilize the skeleton against pressure and shearing forces. In the entire skeleton, about 100 g ionic calcium is absorbed with carbonate or phosphate radicles. A rapid exchange of calcium ions with those absorbed onto the crystal surfaces is necessary to maintain a calcium level in the serum which is essential to life. The calcium ions embedded in the surface of the crystal lattice are responsible for the lesser and slower exchange.

Histologically this remodeling appears as bone trabeculae of varying width. In Fig. 13 osteosderotically widened trabeculae (1) lie next to narrow trabeculae (2). All trabeculae have smooth borders and show no leading edges of deposition or layers of osteoblasts, which is an indieation of slow bone replacement. According to FROST (1966) a threefold system of surface remodeling must be assumed, in whieh anatomically and functionally different types of bone cell take part: 1. periosteal deposition, 2.

18. Normal femoral neck (maceration specimen) Fig. 19. Normal femoral neck (radiograph) 16 2 Normal Anatomy and Histology and, continuous therewith, the shaft of the femur (6). The density of the cancellous scaffolding is remarkably homogeneous. All bones are surrounded by a "frame" of cortical bone (compacta). Internally, the bone is filled with cancellous scaffolding, within which the narrow trabeculae intertwine with one another. In bone subjected to a particular stress the load-carrying spongiosa is more strongly developed than the rest of the "supporting spongiosa".

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