All About Osteoarthritis: The Definitive Resource for by Nancy E. Lane

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By Nancy E. Lane

Osteoarthritis afflicts approximately 25 million humans within the United States--two-thirds of everyone over 65--and the numbers will simply develop within the coming years as child boomers age. but few that suffer from this illness understand a lot approximately it--how to alleviate the ache, what routines may help reduce their discomfort, tips on how to decrease on visits to the surgeon. In All approximately Osteoarthritis, prime specialists at the disease--Nancy E. Lane and Daniel J. Wallace--join forces to supply the main up to date and entire dialogue of osteoarthritis on hand, explaining what osteoarthritis is, how sufferers can assist themselves, and the way to discover the easiest assets to control the disease. The authors provide info in a transparent and available type, with special illustrations displaying how key joints--knees, hips, arms, backs, palms, and necks--degenerate. They take readers during the steps of prognosis, how the physique is affected, and how you can deal with the affliction. In easy language, they describe all the demonstrated cures, together with new drugs and their unintended effects, and aid readers make sure while surgical procedure might be helpful. The authors additionally learn replacement remedies, clarifying which paintings, which can paintings, and which certainly don't. they usually define contemporary advances within the box and speak about the place those breakthroughs could lead us. whereas osteoarthritis so much acutely impacts the aged, it starts off years prior to, and lots of humans endure the aches and pains of the good earlier than previous age. For getting older child boomers, a lot may be performed earlier than osteoarthritis turns into persistent and debilitating. This accomplished advisor will supply an outstanding source for sufferers and their households, caregivers, and doctors.

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While proteoglycans are the shock absorbers of the joint, collagen is a strong fibrous protein provid­ ing the main framework for cartilage. Collagen in the joint forms a structure like a net, to hold the proteoglycans and water. This net pro­ vides cartilage with its shape and tensile strength. Since collagen is a very stiff material, proteoglycans spread throughout the collagen net are flex­ ible, and give cartilage its ability to stretch with movement. Cartilage is an amazing physiologically active material.

The other important function of cartilage is as a lubricant. Like oil, its slipperiness allows joint surfaces to slide back and forth with very little friction. While proteoglycans are the shock absorbers of the joint, collagen is a strong fibrous protein provid­ ing the main framework for cartilage. Collagen in the joint forms a structure like a net, to hold the proteoglycans and water. This net pro­ vides cartilage with its shape and tensile strength. Since collagen is a very stiff material, proteoglycans spread throughout the collagen net are flex­ ible, and give cartilage its ability to stretch with movement.

If we are ever to have a treatment to prevent the progression of osteoarthritis, it will most likely need to have effects on both the bone and the cartilage. DO MENOPAUSE AND HORMONES INFLUENCE BONE METABOLISM? There are times in one's life that bone is more active than other times. For example, when women start menopause and their estrogen levels decrease, bone turnover increases. Bone resorption by the osteoclasts is faster and more efficient than bone formation, and therefore more bone is lost than is formed for each remodeling cycle.

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